Product Details
Description
Amoxycillin Is A Semi-Synthetic Antibiotic, An Analog Of Ampicillin, With A Broad Spectrum Of Bactericidal Activity Against Many Gram-Positive And Gram-Negative Microorganisms. Amoxycillin Is Bactericidal Against Susceptible Organisms During The Stage Of Active Multiplication. It Acts Through The Inhibition Of Biosynthesis Of Cell Wall Mucopeptides. Moxidad Capsules Competitively Inhibit Penicillin Binding Proteins, Leading To Upregulation Of Autolytic Enzymes And Inhibition Of Cell Wall Synthesis. Moxidad Capsules Has A Long Duration Of Action As It Is Usually Given Twice Daily. Moxidad Capsules Has A Wide Therapeutic Range As Mild Overdoses Are Not Associated With Significant Toxicity. Patients Should Be Counselled Regarding The Risk Of Anaphylaxis, Clostridium Difficile Infections, And Bacterial Resistance.
Features &Amp; Benefits
Moxidad Capsules Competitively Inhibits Penicillin-Binding Protein 1 And Other High Molecular Weight Penicillin Binding Proteins.
Penicillin Bind Proteins Are Responsible For Glycosyltransferase And Transpeptidase Reactions That Lead To Cross-Linking Of D-Alanine And D-Aspartic Acid In Bacterial Cell Walls.
Without The Action Of Penicillin Binding Proteins, Bacteria Upregulate Autolytic Enzymes And Are Unable To Build And Repair The Cell Wall, Leading To Bacteriocidal Action.
Moxidad Capsules Is Used For The Treatment Of The Following Bacterial Infections When Caused By Susceptible Organisms:
Respiratory Tract, Ent Infections: Acute And Chronic Bronchitis, Pneumonia, Otitis Media, Sinusitis, Tonsillitis, Pharyngitis &Amp; Laryngitis, Lobar &Amp; Bronchopneumonia, Chronic Bronchial Sepsis.
Urinary Tract Infections: Pyelonephritis, Cystitis And Urethritis.
Obstetric &Amp; Gynaecological Infections: Bacteriuria In Pregnancy, Septic Abortion, Intra-Abdominal Sepsis And Puerperal Sepsis.
Gastro-Intestinal Infections: Typhoid And Paratyphoid.
Skin &Amp; Soft Tissue Infections: Cellulitis, Infected Wounds And Abscesses.
Generalized Infections: Septicemia, Bacterial Endocarditis, Meningitis, Peritonitis And Osteomyelitis.
Venereal Infections: Gonorrhea And Syphilis. Moxidad Capsules May Also Be Used As Prophylactic Cover For Patients At Risk Of Developing Endocarditis When Undergoing Dental Surgery.
Caution
Side Effects Are Mild, Rare And Infrequent. As With Other Penicillins, It May Induce Diarrhea, Indigestion Or Skin Rashes That Usually Stop During Treatment And Rarely Calls For Discontinuation Of Therapy. In Renal Impairment, The Excretion Of Antibiotic Will Be Delayed And Depending On The Degree Of Impairment It May Be Necessary To Reduce The Total Daily Dose.
How To Use
Moxidad Capsules Dosage Ear/Nose/Throat Infection (Mild To Moderate): Adult: 500 Mg Every 12 Hours Or 250 Mg Every 8 Hours. Children: 25 Mg/Kg/Day In Divided Doses Every 12 Hours Or 20 Mg/Kg/Day In Divided Doses Every 8 Hours. Ear/Nose/Throat Infection (Severe): Adult: 875 Mg Every 12 Hours Or 500 Mg Every 8 Hours. Children: 45 Mg/Kg/Day In Divided Doses Every 12 Hours Or 40 Mg/Kg/Day In Divided Doses Every 8 Hours. Lower Respiratory Tract Infection (Mild/ Moderate/ Severe):. Adult: 875 Mg Every 12 Hours Or 500 Mg Every 8 Hours. Children: 45 Mg/Kg/Day In Divided Doses Every 12 Hours Or 40 Mg/Kg/Day In Divided Doses Every 8 Hours. Skin/Skin Structure Infection (Mild/Moderate): Adult: 500 Mg Every 12 Hours Or 250 Mg Every 8 Hours Children: 25 Mg/Kg/Day In Divided Doses Every 12 Hours Or 20 Mg/Kg/Day In Divided Doses Every 8 Hours. Skin/Skin Structure Infection (Severe): Adult: 875 Mg Every 12 Hours Or 500 Mg Every 8 Hours. Children: 45 Mg/Kg/Day In Divided Doses Every 12 Hours Or 40 Mg/Kg/Day In Divided Doses Every 8 Hours. Genitourinary Tract Infection (Mild/ Moderate): Adult: 500 Mg Every 12 Hours Or 250 Mg Every 8 Hours. Children: 25 Mg/Kg/Day In Divided Doses Every 12 Hours Or 20 Mg/Kg/Day In Divided Doses Every 8 Hours. Genitourinary Tract Infection (Severe): Adult: 875 Mg Every 12 Hours Or 500 Mg Every 8 Hours. Children: 45 Mg/Kg/Day In Divided Doses Every 12 Hours Or 40 Mg/Kg/Day In Divided Doses Every 8 Hours. Gonorrhea, Acute, Uncomplicated Ano-Genital, And Urethral Infections In Males And Females: Adult: 3 G As Single Oral Dose. Prepubertal Children: 50 Mg/Kg/Amoxycillin, Combined With 25 Mg/Kg Probenecid As A Single Dose. Since Probenecid Is Contraindicated In Children Under 2 Years, Do Not Use This Regimen In These Cases.